I'm running Fedora 24 with recent Wayland. I tried to run Team Fortress 2. Everything is fine up to the point where you get into 3D rendered part. The mouse pointer control would go nuts and just jerk screen at extreme angles.
I'm aware that source games use mouse pointer retraction technique, to fix mouse pointer at screen center at the end of each frame. Seems like the game fails to do that and mouse cursor just strolling around the screen makes calculations break.
*** This bug has been marked as a duplicate of bug 84644 ***